Lots of opening games in Tennessee last night. These HS games may be the canary in the coal mine for Big 12/SEC/ACC football.

Jack Bauer said:

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This is the problem with a demand economy.

https://bgr.com/2020/08/23/coronavirus-drug-news-apilimod-vacuolin-1-clinical-trial/

Doctors found a new drug that might block coronavirus infections

• A new coronavirus drug type is in clinical trials, with researchers studying its efficacy at blocking the virus from infecting cells.

• PIKfyve kinase inhibitors like vacuolin-1 and apilimod have been found in lab tests to block the SARS-CoV-2 virus from infecting human cells.

• Scientists are now looking to replicate the same results in human trials.

Of course not, because this is all a political game.

Jack Bauer said:

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Of course not, because this is all a political game.

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And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

quash said:

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Jack Bauer said:

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Of course not, because this is all a political game.

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And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

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You spelled vapid wrong

trey3216 said:

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quash said:

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Jack Bauer said:

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Of course not, because this is all a political game.

---

And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

---

You spelled vapid wrong

---

Um...what does this have to do with the CDC?

Governor Cuomo Announces Individuals Traveling to New York Will Be Required to Quarantine for 14 Days

DOOMED!!!!! What a bunch of crap. Fortunately, this will all be over soon.

Jack Bauer said:

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trey3216 said:

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quash said:

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Jack Bauer said:

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Of course not, because this is all a political game.

---

And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

---

You spelled vapid wrong

---

Um...what does this have to do with the CDC?

Governor Cuomo Announces Individuals Traveling to New York Will Be Required to Quarantine for 14 Days

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You said beautiful women. I was stating that the Hollywood types are vapid. Cmon man

trey3216 said:

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Jack Bauer said:

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trey3216 said:

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quash said:

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Jack Bauer said:

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Of course not, because this is all a political game.

---

And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

---

You spelled vapid wrong

---

Um...what does this have to do with the CDC?

Governor Cuomo Announces Individuals Traveling to New York Will Be Required to Quarantine for 14 Days

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You said beautiful women. I was stating that the Hollywood types are valid. Cmon man

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That wasn't me
That was quash.

And my reply was to him too, not you.

Jack Bauer said:

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trey3216 said:

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Jack Bauer said:

---

trey3216 said:

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quash said:

---

Jack Bauer said:

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Of course not, because this is all a political game.

---

And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

---

You spelled vapid wrong

---

Um...what does this have to do with the CDC?

Governor Cuomo Announces Individuals Traveling to New York Will Be Required to Quarantine for 14 Days

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You said beautiful women. I was stating that the Hollywood types are valid. Cmon man

---

That wasn't me
That was quash.

And my reply was to him too, not you.

---

then why did you quote me?

trey3216 said:

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Jack Bauer said:

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trey3216 said:

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quash said:

---

Jack Bauer said:

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Of course not, because this is all a political game.

---

And because the CDC dropped the requirement for everybody, not just celebrities. But post some more tweets of beautiful women.

---

You spelled vapid wrong

---

Um...what does this have to do with the CDC?

Governor Cuomo Announces Individuals Traveling to New York Will Be Required to Quarantine for 14 Days

---

You said beautiful women. I was stating that the Hollywood types are vapid. Cmon man

---

https://www.bloomberg.com/news/articles/2020-08-25/sanchez-rejects-new-spanish-lockdown-amid-surge-in-virus-cases

Quote:

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(Bloomberg) --

Spanish Prime Minister Pedro Sanchez rejected calls for a new national lockdown as the nation reemerges as the epicenter of the coronavirus pandemic in Europe.

---

https://www.nytimes.com/2020/07/23/world/europe/spain-coronavirus-reopening.html

Quote:

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Spain lifted a nationwide state of emergency on June 21 as it emerged from a strict three-month lockdown imposed to gain control over one of Europe's worst outbreaks. The rapid spread of the virus in Spain left some 28,400 people dead by the official count almost surely understated with most of them over the age of 70.

---

Quote:

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Since then, new coronavirus cases have quadrupled now concentrated among young people as the left-wing coalition government of Prime Minister Pedro Snchez returned responsibility for a safe reopening to Spain's regions. That has made Spain a mosaic of new rules some less stringent or more loosely enforced than others and an uneven patchwork of successes mixed with alarming failures.

Several other European countries, from Portugal to Germany, have faced significant local outbreaks after coming out of lockdown, but most of those were more limited in scale and snuffed out relatively quickly. Authorities isolated pockets of new cases and traced those who may have been exposed.

---

Schools: Germany

https://www.cbsnews.com/news/coronavirus-school-germany-no-outbreaks/

Quote:

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Crucially, two weeks in, testing has shown no evidence of anyone contracting the coronavirus within a school.

In most cases, however, the schools had only one student or teacher with an infection, and in all of the cases the infections are believed to have come from outside the schools. While a couple closed for a day to wait for test results on some students or staff, none of Berlin's schools have shut back down completely, and the vast majority in the region more than 800 have reported no cases.

Germany's politicians widely agree that students must be allowed to return to schools, and United Nations Secretary-General Antonio Guterres has warned that if governments don't prioritize that in-class learning, the could face "a catastrophe for an entire generation."

---

France

https://www.france24.com/en/20200823-france-records-post-lockdown-daily-record-of-4-897-new-covid-19-cases

France records post-lockdown daily record of 4,897 new Covid-19 cases

The coronavirus is circulating four times more among people under 40 in France than among over 65-year-olds, Vran said in an interview with France's Journal Du Dimanche (JDD) published on Sunday, adding that the higher number of cases being detected was not solely down to more testing.

Jacques Strap said:

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https://www.bloomberg.com/news/articles/2020-08-25/sanchez-rejects-new-spanish-lockdown-amid-surge-in-virus-cases

Quote:

---

(Bloomberg) --

Spanish Prime Minister Pedro Sanchez rejected calls for a new national lockdown as the nation reemerges as the epicenter of the coronavirus pandemic in Europe.

---

https://www.nytimes.com/2020/07/23/world/europe/spain-coronavirus-reopening.html

Quote:

---

Spain lifted a nationwide state of emergency on June 21 as it emerged from a strict three-month lockdown imposed to gain control over one of Europe's worst outbreaks. The rapid spread of the virus in Spain left some 28,400 people dead by the official count almost surely understated with most of them over the age of 70.

---

Quote:

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Since then, new coronavirus cases have quadrupled now concentrated among young people as the left-wing coalition government of Prime Minister Pedro Snchez returned responsibility for a safe reopening to Spain's regions. That has made Spain a mosaic of new rules some less stringent or more loosely enforced than others and an uneven patchwork of successes mixed with alarming failures.

Several other European countries, from Portugal to Germany, have faced significant local outbreaks after coming out of lockdown, but most of those were more limited in scale and snuffed out relatively quickly. Authorities isolated pockets of new cases and traced those who may have been exposed.

---

---

it's reports like this that show infection as a failure but infection is not a necessarily a failure. Virus gonna virus. An avoidable death is a failure but the current death rate in Spain shows that this is not an issue at this time

Gruvin said:

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Jacques Strap said:

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https://www.bloomberg.com/news/articles/2020-08-25/sanchez-rejects-new-spanish-lockdown-amid-surge-in-virus-cases

Quote:

---

(Bloomberg) --

Spanish Prime Minister Pedro Sanchez rejected calls for a new national lockdown as the nation reemerges as the epicenter of the coronavirus pandemic in Europe.

---

https://www.nytimes.com/2020/07/23/world/europe/spain-coronavirus-reopening.html

Quote:

---

Spain lifted a nationwide state of emergency on June 21 as it emerged from a strict three-month lockdown imposed to gain control over one of Europe's worst outbreaks. The rapid spread of the virus in Spain left some 28,400 people dead by the official count almost surely understated with most of them over the age of 70.

---

Quote:

---

Since then, new coronavirus cases have quadrupled now concentrated among young people as the left-wing coalition government of Prime Minister Pedro Snchez returned responsibility for a safe reopening to Spain's regions. That has made Spain a mosaic of new rules some less stringent or more loosely enforced than others and an uneven patchwork of successes mixed with alarming failures.

Several other European countries, from Portugal to Germany, have faced significant local outbreaks after coming out of lockdown, but most of those were more limited in scale and snuffed out relatively quickly. Authorities isolated pockets of new cases and traced those who may have been exposed.

---

---

it's reports like this that show infection as a failure but infection is not a necessarily a failure. Virus gonna virus. An avoidable death is a failure but the current death rate in Spain shows that this is not an issue at this time

---

Agree. It looks like Spain has joined the "controlled burn" movement... you open as much as you can without overwhelming hospitals.

FWIW

https://www.msn.com/en-us/news/world/china-says-it-began-public-use-of-covid-19-vaccine-a-month-ago-bypassing-clinical-trials/ar-BB18j82t?li=BBnb7Kz

China says it began public use of covid-19 vaccine a month ago, bypassing clinical trials

China is claiming the dubious honor of the first nation to roll out an experimental coronavirus vaccine for public use, saying it began inoculating high-risk groups in late July.

For those keeping score, that would put Beijing's civilian rollout three weeks earlier than Russia's, with neither vaccine having yet passed standard clinical trials. Beijing health officials said Saturday they began dosing some medical workers and state-owned enterprise employees with an experimental covid-19 vaccine in late July under "urgent use" protocols.

The Beijing announcement followed a diplomatic controversy last week, when Papua New Guinea said it had turned back a group of Chinese miners who had received an experimental coronavirus vaccine.

8-25-2020 update





Texas Medical Center
https://www.tmc.edu/coronavirus-updates/

Houston Methodist "COVID-19 Cases by Day". Click scroll to 2nd chart.
https://www.houstonmethodist.org/-/media/pdf/for-patients/Coronavirus/covid-19-stats.ashx

Death rates from coronavirus (COVID-19) in the United States (per 100,000 people)
https://www.statista.com/statistics/1109011/coronavirus-covid19-death-rates-us-by-state/
---------
NJ 180
NY 169
FL 48
TX 40
CA 31

Total number of cases of coronavirus (COVID-19) in the United States by state
https://www.statista.com/statistics/1102807/coronavirus-covid19-cases-number-us-americans-by-state/
-----
CA 670k (39.5M population)
FL 601k (21.4M)
TX 594k (29M)
NY 429k (19.4M) (Case count may be too low due to lack of testing availability in March/April)
GA 253k (10.6M)

Herd Immunity? (Cases x10 CDC multiplier) / Population
https://www.washingtonpost.com/health/2020/06/25/coronavirus-cases-10-times-larger/
(Multipler range may be 6 to 24 https://www.statnews.com/2020/07/21/cdc-study-actual-covid-19-cases/ )
https://www.nytimes.com/2020/08/17/health/coronavirus-herd-immunity.html
CA 17%
FL 28%
TX 20%
NY 22%
GA 24%


Daily confirmed COVID-19 cases and deaths, United States
https://ourworldindata.org/grapher/daily-covid-cases-deaths?time=2020-01-25..&country=~USA

U.S. seven-day average of new coronavirus cases (scroll for chart update)
https://www.cnbc.com/2020/07/14/us-seven-day-average-of-new-coronavirus-cases-surpass-60000-for-the-first-time.html

Where is the graph that shows the cases dropped after mandatory masking?

Virus gonna virus South Korean style. Will they join the "controlled burn" club, or will they stick with contact tracing and lockdowns?

https://news.yahoo.com/south-korea-brink-nationwide-virus-094757850.html

South Korea on brink of nationwide virus outbreak, officials warn

South Korea, a country held up as a model for its response to Covid-19, is on the brink of a new nationwide outbreak, according to officials.

The latest outbreak of coronavirus cases centred around a right-wing Presbyterian church has spread to all 17 provinces throughout the country for the first time.
Each day brings a new three digit virus total.

Social distancing rules have been stepped up. Masks are now mandatory in Seoul. The government is also considering whether to close schools and businesses.

The Korea Centers for Disease Control and Prevention (KCDC) has admitted that about 20% of all new cases are of unknown origin - despite the country's efficient contact tracing system which can track down around 1,000 potentially infected patients in an hour.

efficient...

Jacques Strap said:

---

Virus gonna virus South Korean style. Will they join the "controlled burn" club, or will they stick with contact tracing and lockdowns?

https://news.yahoo.com/south-korea-brink-nationwide-virus-094757850.html

South Korea on brink of nationwide virus outbreak, officials warn

South Korea, a country held up as a model for its response to Covid-19, is on the brink of a new nationwide outbreak, according to officials.

The latest outbreak of coronavirus cases centred around a right-wing Presbyterian church has spread to all 17 provinces throughout the country for the first time.
Each day brings a new three digit virus total.

Social distancing rules have been stepped up. Masks are now mandatory in Seoul. The government is also considering whether to close schools and businesses.

The Korea Centers for Disease Control and Prevention (KCDC) has admitted that about 20% of all new cases are of unknown origin - despite the country's efficient contact tracing system which can track down around 1,000 potentially infected patients in an hour.

efficient...

---

If it came from the Presbyterians, the outcome is preordained no matter what the government tries to do.

Jacques Strap said:

---

Virus gonna virus South Korean style. Will they join the "controlled burn" club, or will they stick with contact tracing and lockdowns?

https://news.yahoo.com/south-korea-brink-nationwide-virus-094757850.html

South Korea on brink of nationwide virus outbreak, officials warn

South Korea, a country held up as a model for its response to Covid-19, is on the brink of a new nationwide outbreak, according to officials.

The latest outbreak of coronavirus cases centred around a right-wing Presbyterian church has spread to all 17 provinces throughout the country for the first time.
Each day brings a new three digit virus total.

Social distancing rules have been stepped up. Masks are now mandatory in Seoul. The government is also considering whether to close schools and businesses.

The Korea Centers for Disease Control and Prevention (KCDC) has admitted that about 20% of all new cases are of unknown origin - despite the country's efficient contact tracing system which can track down around 1,000 potentially infected patients in an hour.

efficient...

---

It's a relative term: who is doing it more efficiently?

quash said:

---

Jacques Strap said:

---

Virus gonna virus South Korean style. Will they join the "controlled burn" club, or will they stick with contact tracing and lockdowns?

https://news.yahoo.com/south-korea-brink-nationwide-virus-094757850.html

South Korea on brink of nationwide virus outbreak, officials warn

South Korea, a country held up as a model for its response to Covid-19, is on the brink of a new nationwide outbreak, according to officials.

The latest outbreak of coronavirus cases centred around a right-wing Presbyterian church has spread to all 17 provinces throughout the country for the first time.
Each day brings a new three digit virus total.

Social distancing rules have been stepped up. Masks are now mandatory in Seoul. The government is also considering whether to close schools and businesses.

The Korea Centers for Disease Control and Prevention (KCDC) has admitted that about 20% of all new cases are of unknown origin - despite the country's efficient contact tracing system which can track down around 1,000 potentially infected patients in an hour.

efficient...

---

It's a relative term: who is doing it more efficiently?

---

How can you efficiently track asymptomatic cases?

This was actually the "Old Thinking" prior to 2020.

https://www.wsj.com/articles/covid-lockdowns-economy-pandemic-recession-business-shutdown-sweden-coronavirus-11598281419

New Thinking on Covid Lockdowns: They're Overly Blunt and Costly

Quote:

---

In response to the novel and deadly coronavirus, many governments deployed draconian tactics never used in modern times: severe and broad restrictions on daily activity that helped send the world into its deepest peacetime slump since the Great Depression.

The equivalent of 400 million jobs have been lost world-wide, 13 million in the U.S. alone. Global output is on track to fall 5% this year, far worse than during the financial crisis, according to the International Monetary Fund.

Despite this steep price, few policy makers felt they had a choice, seeing the economic crisis as a side effect of the health crisis. They ordered nonessential businesses closed and told people to stay home, all without the extensive analysis of benefits and risks that usually precedes a new medical treatment.
There wasn't time to gather that sort of evidence: Faced with a poorly understood and rapidly spreading pathogen, they prioritized saving lives.

Five months later, the evidence suggests lockdowns were an overly blunt and economically costly tool. They are politically difficult to keep in place for long enough to stamp out the virus. The evidence also points to alternative strategies that could slow the spread of the epidemic at much less cost. As cases flare up throughout the U.S., some experts are urging policy makers to pursue these more targeted restrictions and interventions rather than another crippling round of lockdowns.

---

Jacques Strap said:

---

quash said:

---

Jacques Strap said:

---

Virus gonna virus South Korean style. Will they join the "controlled burn" club, or will they stick with contact tracing and lockdowns?

https://news.yahoo.com/south-korea-brink-nationwide-virus-094757850.html

South Korea on brink of nationwide virus outbreak, officials warn

South Korea, a country held up as a model for its response to Covid-19, is on the brink of a new nationwide outbreak, according to officials.

The latest outbreak of coronavirus cases centred around a right-wing Presbyterian church has spread to all 17 provinces throughout the country for the first time.
Each day brings a new three digit virus total.

Social distancing rules have been stepped up. Masks are now mandatory in Seoul. The government is also considering whether to close schools and businesses.

The Korea Centers for Disease Control and Prevention (KCDC) has admitted that about 20% of all new cases are of unknown origin - despite the country's efficient contact tracing system which can track down around 1,000 potentially infected patients in an hour.

efficient...

---

It's a relative term: who is doing it more efficiently?

---

How can you efficiently track asymptomatic cases?

---

S. Korea had a robust testing program, working hand in hand with the strict tracing. If a trace suggested you had contact you got tested and were quarantined until the results came back. Pretty efficient. Anybody doing better than 80%?

Everything is mere chatter until a viable vaccine is widely available .

South Korea

https://www.reuters.com/article/us-health-coronavirus-southkorea/south-korea-orders-striking-doctors-back-to-work-amid-surge-in-coronavirus-cases-idUSKBN25M048

South Korea orders striking doctors back to work amid surge in coronavirus cases

Jacques Strap said:

---

Belgium

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants
24 August 2020


Hydroxychloroquine (HCQ) 2400 mg during 5 days was used in Belgium for COVID-19

Impact of HCQ on mortality among 8075 patients with COVID-19 was assessed

Lower mortality in HCQ-treated patients as compared to supportive care

Lower mortality is irrespective of symptoms duration

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

---

nah... orange man bad

Jacques Strap said:

---

Belgium

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants
24 August 2020


Hydroxychloroquine (HCQ) 2400 mg during 5 days was used in Belgium for COVID-19

Impact of HCQ on mortality among 8075 patients with COVID-19 was assessed

Lower mortality in HCQ-treated patients as compared to supportive care

Lower mortality is irrespective of symptoms duration

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

---

Do you even #science bruh?

Jacques Strap said:

---

Belgium

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants
24 August 2020


Hydroxychloroquine (HCQ) 2400 mg during 5 days was used in Belgium for COVID-19

Impact of HCQ on mortality among 8075 patients with COVID-19 was assessed

Lower mortality in HCQ-treated patients as compared to supportive care

Lower mortality is irrespective of symptoms duration

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

---

Lots of questions:

First, my understanding is that if HCQ is to be effective, it has to be used early. If the Belgian doctors were operating under the same understanding, the reason for not prescribing may have been that the disease had progressed past the expected usefulness of the HCQ. That would create an apples and oranges scenario between the prescribed and non-prescribed populations.

Second, and likewise, does the HCQ prescription represent a generally more advanced and aggressive overall therapy with more resources, also creating apples and oranges?

Third, what changes in mortality would result from placebo use?

Booray said:

---

Jacques Strap said:

---

Belgium

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants
24 August 2020


Hydroxychloroquine (HCQ) 2400 mg during 5 days was used in Belgium for COVID-19

Impact of HCQ on mortality among 8075 patients with COVID-19 was assessed

Lower mortality in HCQ-treated patients as compared to supportive care

Lower mortality is irrespective of symptoms duration

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

---

Lots of questions:

First, my understanding is that if HCQ is to be effective, it has to be used early. If the Belgian doctors were operating under the same understanding, the reason for not prescribing may have been that the disease had progressed past the expected usefulness of the HCQ. That would create an apples and oranges scenario between the prescribed and non-prescribed populations.

Second, and likewise, does the HCQ prescription represent a generally more advanced and aggressive overall therapy with more resources, also creating apples and oranges?

Third, what changes in mortality would result from placebo use?

---

Retrospective study, so it includes the usual limitation of that type of study. The PDF has a lot of additional information. I thought the results were interesting and aligned with the Henry Ford Hospital Study. I'm not a fan of the use of placebos in a COVID study with HCQ because you must withhold potentially life-saving medical treatment from some people. So, a study like that risks killing people to prove HCQ works.

If people don't want to take HCQ that's their call. Just wanted to post this recent study for those in doubt so to help them make up their own mind in consultation with their Doctor.